LymphedemaV1, Main, Exploration, bibRecord, 003896

Alterations of lymph flow after lymphadenectomy in rats revealed by real time fluorescence imaging system.

Identifieur interne : 003896 ( Main/Exploration ); précédent : 003895; suivant : 003897

Alterations of lymph flow after lymphadenectomy in rats revealed by real time fluorescence imaging system.

Auteurs : Y. Takeno [Japon] ; E. Fujimoto

Source :

Lymphology [ 0024-7766 ] ; 2013.

RBID : pubmed:23930437

Descripteurs français

KwdFr :
- Agents colorants, Animaux, Lymphadénectomie (effets indésirables), Lymphe (sécrétion), Lymphoedème (diagnostic), Lymphoedème (métabolisme), Lymphoedème (étiologie), Lymphographie, Mâle, Noeuds lymphatiques (), Rat Wistar, Rats, Vaisseaux lymphatiques (anatomopathologie), Vert indocyanine.
MESH :
- anatomopathologie : Vaisseaux lymphatiques.
- diagnostic : Lymphoedème.
- effets indésirables : Lymphadénectomie.
- métabolisme : Lymphoedème.
- sécrétion : Lymphe.
- étiologie : Lymphoedème.
- Agents colorants, Animaux, Lymphographie, Mâle, Noeuds lymphatiques, Rat Wistar, Rats, Vert indocyanine.

English descriptors

KwdEn :
- Animals, Coloring Agents, Indocyanine Green, Lymph (secretion), Lymph Node Excision (adverse effects), Lymph Nodes (surgery), Lymphatic Vessels (pathology), Lymphedema (diagnosis), Lymphedema (etiology), Lymphedema (metabolism), Lymphography, Male, Rats, Rats, Wistar.
MESH :
- chemical : Coloring Agents, Indocyanine Green.
- adverse effects : Lymph Node Excision.
- diagnosis : Lymphedema.
- etiology : Lymphedema.
- metabolism : Lymphedema.
- pathology : Lymphatic Vessels.
- secretion : Lymph.
- surgery : Lymph Nodes.
- Animals, Lymphography, Male, Rats, Rats, Wistar.

Abstract

Secondary lymphedema is one of the sequella of cancer treatment that in inadequately understood. The purpose of the present study is to investigate lymphedema formation and to explore the escape routes for excess interstitial fluid using lymphadenectomy in a rat model. In twelve Wistar rats, lymph nodes in the right inguinal and popliteal fossas were completely removed and lymph vessels carefully ligated. After operation, treated hind limbs were evaluated by indocyanine green lymphography and circumferential measurement. Both evaluations were performed from day 3 to ten weeks. Approximately 2 to 3 weeks after operation, a network-like pattern of the fluorescent signal appeared around the surgical site which then transitioned into a linear pattern in the lower abdomen. Videorecordings identified fluorescent flow moving from the lower abdomen to the ipsilateral axillary lymph node and in some rats, the network-like pattern was also observed to pass transversely over the suprapubic region to the contralateral inguinal lymph nodes. The network-like pattern on the lower abdomen and the linear pattern to the axillary fossa were seen continuously to the end of observation. Circumferential measurements of the treated hind limbs increased initially and then declined over time. This imaging system may be useful to detect early changes in lymphatic flow before swelling occurs and further study is needed.

PubMed: 23930437

Affiliations:

Japon

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Alterations of lymph flow after lymphadenectomy in rats revealed by real time fluorescence imaging system.</title>
<author><name sortKey="Takeno, Y" sort="Takeno, Y" uniqKey="Takeno Y" first="Y" last="Takeno">Y. Takeno</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Nursing, Graduate School of Medicine, Nagoya University, Nagoya, Aichi Japan. takeno.yukari@a.mbox.nagoya-u.ac.jp</nlm:affiliation>
<country wicri:rule="url">Japon</country>
</affiliation>
</author>
<author><name sortKey="Fujimoto, E" sort="Fujimoto, E" uniqKey="Fujimoto E" first="E" last="Fujimoto">E. Fujimoto</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2013">2013</date>
<idno type="RBID">pubmed:23930437</idno>
<idno type="pmid">23930437</idno>
<idno type="wicri:Area/PubMed/Corpus">001979</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001979</idno>
<idno type="wicri:Area/PubMed/Curation">001979</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001979</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001979</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001979</idno>
<idno type="wicri:Area/Ncbi/Merge">005C27</idno>
<idno type="wicri:Area/Ncbi/Curation">005C27</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005C27</idno>
<idno type="wicri:doubleKey">0024-7766:2013:Takeno Y:alterations:of:lymph</idno>
<idno type="wicri:Area/Main/Merge">003904</idno>
<idno type="wicri:Area/Main/Curation">003896</idno>
<idno type="wicri:Area/Main/Exploration">003896</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Alterations of lymph flow after lymphadenectomy in rats revealed by real time fluorescence imaging system.</title>
<author><name sortKey="Takeno, Y" sort="Takeno, Y" uniqKey="Takeno Y" first="Y" last="Takeno">Y. Takeno</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Nursing, Graduate School of Medicine, Nagoya University, Nagoya, Aichi Japan. takeno.yukari@a.mbox.nagoya-u.ac.jp</nlm:affiliation>
<country wicri:rule="url">Japon</country>
</affiliation>
</author>
<author><name sortKey="Fujimoto, E" sort="Fujimoto, E" uniqKey="Fujimoto E" first="E" last="Fujimoto">E. Fujimoto</name>
</author>
</analytic>
<series><title level="j">Lymphology</title>
<idno type="ISSN">0024-7766</idno>
<imprint><date when="2013" type="published">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Coloring Agents</term>
<term>Indocyanine Green</term>
<term>Lymph (secretion)</term>
<term>Lymph Node Excision (adverse effects)</term>
<term>Lymph Nodes (surgery)</term>
<term>Lymphatic Vessels (pathology)</term>
<term>Lymphedema (diagnosis)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (metabolism)</term>
<term>Lymphography</term>
<term>Male</term>
<term>Rats</term>
<term>Rats, Wistar</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Agents colorants</term>
<term>Animaux</term>
<term>Lymphadénectomie (effets indésirables)</term>
<term>Lymphe (sécrétion)</term>
<term>Lymphoedème (diagnostic)</term>
<term>Lymphoedème (métabolisme)</term>
<term>Lymphoedème (étiologie)</term>
<term>Lymphographie</term>
<term>Mâle</term>
<term>Noeuds lymphatiques ()</term>
<term>Rat Wistar</term>
<term>Rats</term>
<term>Vaisseaux lymphatiques (anatomopathologie)</term>
<term>Vert indocyanine</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Coloring Agents</term>
<term>Indocyanine Green</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lymph Node Excision</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Vaisseaux lymphatiques</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Lymphadénectomie</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymphatic Vessels</term>
</keywords>
<keywords scheme="MESH" qualifier="secretion" xml:lang="en"><term>Lymph</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Lymph Nodes</term>
</keywords>
<keywords scheme="MESH" qualifier="sécrétion" xml:lang="fr"><term>Lymphe</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Lymphography</term>
<term>Male</term>
<term>Rats</term>
<term>Rats, Wistar</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Agents colorants</term>
<term>Animaux</term>
<term>Lymphographie</term>
<term>Mâle</term>
<term>Noeuds lymphatiques</term>
<term>Rat Wistar</term>
<term>Rats</term>
<term>Vert indocyanine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Secondary lymphedema is one of the sequella of cancer treatment that in inadequately understood. The purpose of the present study is to investigate lymphedema formation and to explore the escape routes for excess interstitial fluid using lymphadenectomy in a rat model. In twelve Wistar rats, lymph nodes in the right inguinal and popliteal fossas were completely removed and lymph vessels carefully ligated. After operation, treated hind limbs were evaluated by indocyanine green lymphography and circumferential measurement. Both evaluations were performed from day 3 to ten weeks. Approximately 2 to 3 weeks after operation, a network-like pattern of the fluorescent signal appeared around the surgical site which then transitioned into a linear pattern in the lower abdomen. Videorecordings identified fluorescent flow moving from the lower abdomen to the ipsilateral axillary lymph node and in some rats, the network-like pattern was also observed to pass transversely over the suprapubic region to the contralateral inguinal lymph nodes. The network-like pattern on the lower abdomen and the linear pattern to the axillary fossa were seen continuously to the end of observation. Circumferential measurements of the treated hind limbs increased initially and then declined over time. This imaging system may be useful to detect early changes in lymphatic flow before swelling occurs and further study is needed.</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
</country>
</list>
<tree><noCountry><name sortKey="Fujimoto, E" sort="Fujimoto, E" uniqKey="Fujimoto E" first="E" last="Fujimoto">E. Fujimoto</name>
</noCountry>
<country name="Japon"><noRegion><name sortKey="Takeno, Y" sort="Takeno, Y" uniqKey="Takeno Y" first="Y" last="Takeno">Y. Takeno</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003896 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003896 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:23930437
   |texte=   Alterations of lymph flow after lymphadenectomy in rats revealed by real time fluorescence imaging system.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:23930437" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

Alterations of lymph flow after lymphadenectomy in rats revealed by real time fluorescence imaging system.

Alterations of lymph flow after lymphadenectomy in rats revealed by real time fluorescence imaging system.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.